|
Plexiform leiomyoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.
|
31649266 |
2019 |
|
Uterine Fibroids
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.
|
31649266 |
2019 |
|
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation
|
BEFREE |
The variants rs10069690 and rs2853676 were also described as risk factors for BC.
|
29332343 |
2019 |
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs2853676 in TERT could increase the risk of COPD in the dominant model ("C/T-T/T" genotype, p = 0.026) and in the Log-additive model (p = 0.022).
|
31270965 |
2019 |
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The variants rs10069690 and rs2853676 were also described as risk factors for BC.
|
29332343 |
2019 |
|
Giant Cell Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We observed that CXCR4 rs6430612, TERT rs10069690, and rs2853676 as well as VPS34 rs2162440 are significantly associated with GCA development.
|
30900102 |
2019 |
|
Idiopathic Pulmonary Fibrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The minor allele frequencies (MAF) were significantly greater for MUC5B rs868903 (P = 0.042) and TERT rs2853676 (P = 0.041) in IPF than those in healthy controls.
|
31653936 |
2019 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Univariate analyses showed that ACYP2 rs12615793 and TERT rs2853676 loci affected progression-free survival in glioma patients; both ZNF208 rs8105767 and ACYP2 rs843720 affected the OS of patients with low-grade gliomas.
|
28985021 |
2017 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Our study indicates that TERT rs2853676 polymorphisms correlate with glioma survival and recurrence rates in a Chinese population, which suggests that they could potentially serve as prognostic markers in glioma patients.
|
27655710 |
2016 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that the TERT genetic polymorphism rs2853676 is associated with increased risk of glioma, lung adenocarcinoma and ovarian cancer among Caucasians.
|
26042809 |
2015 |
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
A significant association between TERT rs2853676 allele A and cancer susceptibility was demonstrated under a per-allele risk analysis (OR = 1.08, 95% CI = 1.04-1.13).
|
26042809 |
2015 |
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
A significant association between TERT rs2853676 allele A and cancer susceptibility was demonstrated under a per-allele risk analysis (OR = 1.08, 95% CI = 1.04-1.13).
|
26042809 |
2015 |
|
Adenocarcinoma of lung (disorder)
|
|
0.020 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that the TERT genetic polymorphism rs2853676 is associated with increased risk of glioma, lung adenocarcinoma and ovarian cancer among Caucasians.
|
26042809 |
2015 |
|
MYOTONIC DYSTROPHY 1
|
|
0.010 |
GeneticVariation
|
BEFREE |
Chinese polymyositis (PM) patients (n =291), dermatomyositis (DM) patients (n=526) and ethnically-matched healthy controls (n =968) were genotyped for the CCL21 region SNPs (rs951005 and rs2492358), ERBB3 (rs2292239 and rs11171739), and TERT (rs2853676 and rs10069690), by using the Sequenom MassArray system.
|
26320593 |
2015 |
|
Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
Chinese polymyositis (PM) patients (n =291), dermatomyositis (DM) patients (n=526) and ethnically-matched healthy controls (n =968) were genotyped for the CCL21 region SNPs (rs951005 and rs2492358), ERBB3 (rs2292239 and rs11171739), and TERT (rs2853676 and rs10069690), by using the Sequenom MassArray system.
|
26320593 |
2015 |
|
Adult type dermatomyositis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Chinese polymyositis (PM) patients (n =291), dermatomyositis (DM) patients (n=526) and ethnically-matched healthy controls (n =968) were genotyped for the CCL21 region SNPs (rs951005 and rs2492358), ERBB3 (rs2292239 and rs11171739), and TERT (rs2853676 and rs10069690), by using the Sequenom MassArray system.
|
26320593 |
2015 |
|
Dermatomyositis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Chinese polymyositis (PM) patients (n =291), dermatomyositis (DM) patients (n=526) and ethnically-matched healthy controls (n =968) were genotyped for the CCL21 region SNPs (rs951005 and rs2492358), ERBB3 (rs2292239 and rs11171739), and TERT (rs2853676 and rs10069690), by using the Sequenom MassArray system.
|
26320593 |
2015 |
|
Polymyositis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Chinese polymyositis (PM) patients (n =291), dermatomyositis (DM) patients (n=526) and ethnically-matched healthy controls (n =968) were genotyped for the CCL21 region SNPs (rs951005 and rs2492358), ERBB3 (rs2292239 and rs11171739), and TERT (rs2853676 and rs10069690), by using the Sequenom MassArray system.
|
26320593 |
2015 |
|
Adenocarcinoma of lung (disorder)
|
|
0.020 |
GeneticVariation
|
BEFREE |
Gene variations rs2736100 and rs2853676 in TERT and rs401681 and rs31489 in CLPTM1L had significant direct associations on lung adenocarcinoma without indirect effects through nicotine dependence.
|
25233467 |
2014 |
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two glioma risk variants, TERT rs2853676 and CDKN2BAS1 rs4977756, which are located in regions previously associated with lung cancer, were associated with increased risk of adenocarcinoma (OR = 1.16; 95% CI = 1.10 to 1.22; P = 1.1×10(-8)) and squamous cell carcinoma (OR = 1.13; CI = 1.07 to 1.19; P = 2.5×10(-5)), respectively.
|
24681604 |
2014 |
|
Adenocarcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two glioma risk variants, TERT rs2853676 and CDKN2BAS1 rs4977756, which are located in regions previously associated with lung cancer, were associated with increased risk of adenocarcinoma (OR = 1.16; 95% CI = 1.10 to 1.22; P = 1.1×10(-8)) and squamous cell carcinoma (OR = 1.13; CI = 1.07 to 1.19; P = 2.5×10(-5)), respectively.
|
24681604 |
2014 |
|
Nicotine Dependence
|
|
0.010 |
GeneticVariation
|
BEFREE |
Gene variations rs2736100 and rs2853676 in TERT and rs401681 and rs31489 in CLPTM1L had significant direct associations on lung adenocarcinoma without indirect effects through nicotine dependence.
|
25233467 |
2014 |
|
Carcinoma of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two glioma risk variants, TERT rs2853676 and CDKN2BAS1 rs4977756, which are located in regions previously associated with lung cancer, were associated with increased risk of adenocarcinoma (OR = 1.16; 95% CI = 1.10 to 1.22; P = 1.1×10(-8)) and squamous cell carcinoma (OR = 1.13; CI = 1.07 to 1.19; P = 2.5×10(-5)), respectively.
|
24681604 |
2014 |
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two glioma risk variants, TERT rs2853676 and CDKN2BAS1 rs4977756, which are located in regions previously associated with lung cancer, were associated with increased risk of adenocarcinoma (OR = 1.16; 95% CI = 1.10 to 1.22; P = 1.1×10(-8)) and squamous cell carcinoma (OR = 1.13; CI = 1.07 to 1.19; P = 2.5×10(-5)), respectively.
|
24681604 |
2014 |
|
Squamous cell carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two glioma risk variants, TERT rs2853676 and CDKN2BAS1 rs4977756, which are located in regions previously associated with lung cancer, were associated with increased risk of adenocarcinoma (OR = 1.16; 95% CI = 1.10 to 1.22; P = 1.1×10(-8)) and squamous cell carcinoma (OR = 1.13; CI = 1.07 to 1.19; P = 2.5×10(-5)), respectively.
|
24681604 |
2014 |